The hairy problem of epigenetics in evolution.

Anti-inflammatory effects of essential oil, aerial parts and hairy roots extracts of Nepeta pogonosperma on rat brain mixed cells

Background and objectives: Many Nepeta species have been commonly used in Iranian folk medicine as tranquilizer, relaxant, carminative and restorative tonic for nervous and respiratory disorders. Inflammation is a problem in many diseases and has an important role in brain function that can cause neurodegenerative disorders. Inflamed glial cells can exacerbate neurodegenerative disease...

Role of Epigenetics in Biology and Human Diseases

For a long time, scientists have tried to describe disorders just by genetic or environmental factors. However, the role of epigenetics in human diseases has been considered from a half of century ago. In the last decade, this subject has attracted many interests, especially in complicated disorders such as behavior plasticity, memory, cancer, autoimmune disease, and addiction as well as neurod...

Modified Pareto archived evolution strategy for the multi-skill project scheduling problem with generalized precedence relations

In this research, we study the multi-skill resource-constrained project scheduling problem, where there are generalized precedence relations between project activities. Workforces are able to perform one or several skills, and their efficiency improves by repeating their skills. For this problem, a mathematical formulation has been proposed that aims to optimize project completion time, reworki...

Agrobacterium Rhizogenes-mediated Transformation of Peganum multisectum (Maxim) Bobrov and Harmine Production in Hairy Roots

Using Agrobacterium rhizogenes due to create hairy roots is a useful method to product secondary metabolites in many medicinal plants. The transgenic hairy roots were induced from Peganum multisectum (Maxim) Bobrov a medicinally important species, by infecting leaf and stem explant with wild type Agrobacterium rhizogenes strain ATTCC 15834, which led to the induction of hairy roots from 19% of ...

Evolution of the first eigenvalue of buckling problem on Riemannian manifold under Ricci flow

Among the eigenvalue problems of the Laplacian, the biharmonic operator eigenvalue problems are interesting projects because these problems root in physics and geometric analysis. The buckling problem is one of the most important problems in physics, and many studies have been done by the researchers about the solution and the estimate of its eigenvalue. In this paper, first, we obtain the evol...

The Prospects of Epigenetics in Neuroscience